Prosurf® Publicaciones Científicas 2018-01-10T14:13:39+00:00

Publicaciones Científicas.

1.  Nebulised exogenous natural surfactant after cardic surgery.
J L do Campo, E G Bertranou, A De Lorenzi, A A Hager.
The Lancet. 1994; 343(8895): 482.

PAPER (PDF)

2.  Natural surfactant aerosolisation in adult respiratory distress syndrome.
J L do Campo, E Turchetto, E G Bertranou, A A Hager, T De Paoli.
The Lancet. 1994; 344(8919): 413-414.

PAPER (PDF)

3.  Use of lung surfactant –99mTc in lung studies.
Alak , O. Degrossi , H. García del Río, J. Boccio , M. Zubillaga, T. De Paoli, A. Hager, R. Caro.
Nuclear Medicine. Clinic Aspect  (1996). 233-236.

PAPER (PDF)

4.   99mTc-ENS, a New Radiopharmaceutical for Aerial Lung Scintigraphy: Comparative Studies In Rats.
G Calmanovici, M Zubillaga, A Lysionek, A Hager, T De Paoli, M Alak, O Degrossi, H Garcia del Rio, J Nicolini, R Caro and J Boccio.
Nuclear Medicine & Biology. 1998; Vol. 25: 511-513.

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5.  El sistema surfactante pulmonar: Fisiología, patologías asociadas a su alteración y administración exógena como agente terapéutico y de diagnóstico.
G Calmanovici, J Boccio, A Lysionek, M Salgueiro, R Caro, A Hager, T De Paoli, y M Zubillaga.
Acta Phisiol. Pharmacol. Ther. Latinoamericana.(APPTLA) 1998;  48(4): 175-190.

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6.  99mTc-ENS: A New Radiopharmaceutical for aerial Lung Scintigraphy.
G. Calmanovici, M Zubillaga, A Lysionek, A Hager, T De Paoli, M Alak, O  Degrossi, H Garcia del Rio, J Nicolini, R Caro and J Boccio.
Eur. J. Nuclear Medicine. 1998; 25(8): 891.

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7.  99mTc-ENS: A New Radiopharmaceutical for Aerosol Lung Scintigraphy. Comparison Between Different Freeze – Dried Formulations.
G Calmanovici, , J Boccio, A Lysionek, M Salgueiro, A Hager, T De Paoli, M Calcagno, J Nicolini, M Tarlati, R Caro and M Zubillaga.
The Journal of Nuclear Medicine. 1999; Vol.:40, N°:6, 1080-1083.

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8.  99mTc-ENS Ventilation scintigraphy. Preliminary study in human volunteers.
G Calmanovici, , J Boccio, C Goldman, A Hager, T De Paoli, M Alak, O Degrossi, H García del Río, J Nicolini, R  Caro and M Zubillaga.
Nuclear Medicine & Biology.  2000; Vol: 27, pp. 215-218.

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9.  Centellografía aérea pulmonar. Estudio comparativo con 99mTc-ENS y 99mTc-DTPA
G Calmanovici, , J Boccio, C Goldman, A Hager, T De Paoli, M Alak, O Degrossi, H García del Río, J Nicolini, R  Caro and M Zubillaga.
Diagnóstico.  2001; Vol: X, 51-54.

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10.  La medicina nuclear en el diagnóstico de las enfermedades pulmonares.
G Calmanovici, , C Goldman, J Boccio, R  Caro y M Zubillaga.
Revista Farmacéutica. 2001; Vol: 143. 7-14.

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11.  Formas farmacéuticas del surfactante natural exógeno (ENS) para ser utilizado en diagnóstico y terapia.
Calmanovici, C. Goldman, J. Boccio, A. Hager, T. De Paoli, R. Caro y M. Zubillaga.
Revista Farmacéutica. 2002. Vol: 144, 11-14.

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12.  Evaluation of Different Formulations to Lebel Exogenous Natural Surfactant Labeled With (99mTc-ENS). Stability and Toxicity Studies
G Calmanovici, , R. Caro, C Goldman, J Boccio, J. Nicolini, T De Paoli, A Hager, and M Zubillaga.
Alasbimn Journal.  2003; Year: 5, N°: 19.

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13.  Quality control methods for 99mTc-labeled exogenous natural surfactant (99mTc-ENS).
Calmanovici, R. Caro, C. Goldman, N. Leonardi, J. Boccio and M. Zubillaga.
Journal Label. Compd. Radiopharm. 2004, Vol: 47, 47-53.

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14.  99mTc-ENS vs. 99mTc-DTPA as Aerosol Lung Scintiscanning Agents.
Mayosky, G. Saravia, J.O. Nicolini, R. Caro, A. Hager, T. De Paoli, G. Calmanovici and M. Zubillaga.
Alasbimn Journal. April 2004, Year: 6 Nº: 24.

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15.  Quality Control Validation for Exogenous Natural Surfactant Labeled witj 99mTc.
Calmanovici, M. Salgueiro, N. Leonardi, C. Goldman, J. Nicolini, J. Boccio R. Caro, P. Zubata and M. Zubillaga.
Journal of Nuclear Medicine Technology. December 2005, Vol. 33, Number 4, 234-237

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16.  Influence of serum protein and albumin addition on the structure and activity of an exogenous pulmonary surfactant.
María Martínez Sarrasague, Alejandra Cimato, Emilio Rubin de Celis, Graciela Facorro.
Respiratory Physiology & Neurology. 175 (2011) 316 – 321

PAPER (PDF)

17.  Effect of serum proteins on an exogenous pulmonary surfactant: ESR analysis of structural changes and their relation with surfactant activity.
María Martínez Sarrasague, Alejandra Cimato, Emilio Rubin de Celis, Graciela Facorro.
Respiratory Physiology & Neurology. 183 (2012) 48 – 57

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18.  Effect of serum lipoproteins and cholesterol on an exogenous pulmonary surfactant. ESR analysis of structural changes and their relation with surfactant activity.
María Martínez Sarrasague, Alejandra Cimato, Lidia Piehl, Fernando Brites, Graciela Facorro.
Respiratory Physiology & Neurology. 189 (2013) 581 – 587

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19. Analysis of the structure and surfactant activity of novel formulations containing exogenous pulmonary surfactant and glucocorticoids.
Alejandra Cimato, Andres Hoyos Obando, Graciela Facorro, María Martínez Sarrasague.
Respiratory Physiology & Neurology. 233 (2016) 33 – 40

PAPER (PDF)

20. Developing an exogenous pulmonary surfactant-glucocorticoids association: Effect of corticoid concentration on the biophysical properties of the surfactant.
Alejandra Cimato, Graciela Facorro, María Martínez Sarrasague.
Respiratory Physiology & Neurology. 247 (2018) 80 – 86

PAPER (PDF)